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Exploring the mechanism of metformin action in Alzheimer’s disease and type 2 diabetes based on network pharmacology, molecular docking, and molecular dynamic simulation
BACKGROUND: Metformin, which has been shown to be highly effective in treating type 2 diabetes (T2D), is also believed to be valuable for Alzheimer’s disease (AD). Computer simulation techniques have emerged as an innovative approach to explore mechanisms. OBJECTIVE: To study the potential mechanism...
Autores principales: | Shi, Xin, Li, Lingling, Liu, Zhiyao, Wang, Fangqi, Huang, Hailiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540612/ https://www.ncbi.nlm.nih.gov/pubmed/37780174 http://dx.doi.org/10.1177/20420188231187493 |
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