Cargando…

Pre-clinical investigation of liquid sirolimus for local drug delivery

INTRODUCTION: Sirolimus is currently being explored as an alternative drug to paclitaxel for the treatment of peripheral artery disease (PAD). To date, sirolimus has only been used as drug coatings for stents and balloons and no studies have yet demonstrated the delivery of sirolimus in liquid form....

Descripción completa

Detalles Bibliográficos
Autores principales:	Todd, Meagan, Liu, Linda B., Saul, Justin M., Yazdani, Saami K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540618/ https://www.ncbi.nlm.nih.gov/pubmed/37781304 http://dx.doi.org/10.3389/fcvm.2023.1184816

Ejemplares similares

Pre-Clinical Investigation of Liquid Paclitaxel for Local Drug Delivery: A Pilot Study
por: Cawthon, Claire V., et al.
Publicado: (2020)

Pre-Clinical Investigation of Keratose as an Excipient of Drug Coated Balloons
por: Goel, Emily, et al.
Publicado: (2020)

Understanding the Mechanism of Drug Transfer and Retention of Drug-Coated Balloons
por: Villar-Matamoros, Estefanny, et al.
Publicado: (2022)

Clinical outcomes in 995 unselected real-world patients treated with an ultrathin biodegradable polymer-coated sirolimus-eluting stent: 12-month results from the FLEX Registry
por: Lemos, Pedro A, et al.
Publicado: (2016)

Prospective evaluation of an ultrathin strut biodegradable polymer-coated sirolimus-eluting stent: 12 months’ results from the S-FLEX UK registry
por: Choudhury, Anirban, et al.
Publicado: (2019)

Precision delivery of liquid therapy into the arterial wall for the treatment of peripheral arterial disease
por: Atigh, Marzieh K., et al.
Publicado: (2021)

Neoatherosclerosis in Sirolimus-Eluting Stents After Paclitaxel-Coated Ballooning Cannot Be Stabilized Despite PCSK9 Inhibitor Therapy
por: Miyoshi, Toru, et al.
Publicado: (2019)

Immune Checkpoint Inhibitors: Cardiotoxicity in Pre-clinical Models and Clinical Studies
por: Xu, Shirley, et al.
Publicado: (2021)

Nano drugs delivery system: A novel promise for the treatment of atrial fibrillation
por: Wang, Zhengjie, et al.
Publicado: (2022)

Arrhythmogenic Mechanisms in Hypokalaemia: Insights From Pre-clinical Models
por: Tse, Gary, et al.
Publicado: (2021)

Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression
por: Rahman, Karishma, et al.
Publicado: (2018)

De novo Drug Delivery Modalities for Treating Damaged Hearts: Current Challenges and Emerging Solutions
por: Alvi, Syed Baseeruddin, et al.
Publicado: (2021)

Prospective multicentre open-label randomised controlled trial of 3-month versus 12-month dual antiplatelet therapy after implantation of the new generation biodegradable polymer sirolimus TARGET-eluting coronary stent: protocol of the TARGET DAPT trial
por: Yang, Hongbo, et al.
Publicado: (2019)

Association of QT interval-prolonging drugs with clinical trial eligibility in patients with advanced cancer
por: Rowe, Elizabeth J., et al.
Publicado: (2022)

Shockwaves delivery for aortic valve therapy—Realistic perspective for clinical translation?
por: Curini, Lavinia, et al.
Publicado: (2023)

Population and Age-Based Cardiorespiratory Fitness Level Investigation and Automatic Prediction
por: Xiang, Liangliang, et al.
Publicado: (2022)

Risk investigation of in-stent restenosis after initial implantation of intracoronary drug-eluting stent in patients with coronary heart disease
por: Xi, Hongfei, et al.
Publicado: (2023)

Discrete choice experiment to investigate preferences for psychological intervention in cardiac rehabilitation
por: Shields, Gemma E, et al.
Publicado: (2022)

Clinical value of mean platelet volume in predicting and diagnosing pre-eclampsia: a systematic review and meta-analysis
por: Ye, Dan, et al.
Publicado: (2023)

Case report: Diagnosis of apical hypertrophic cardiomyopathy that escaped clinical and echocardiographic investigations for twenty years: Reasons and clinical implications
por: Caiati, Carlo, et al.
Publicado: (2023)

Narrative update of clinical trials with antihypertensive drugs in children and adolescents
por: Redon, Josep, et al.
Publicado: (2022)

Cardiotoxicity of anti-cancer drugs: cellular mechanisms and clinical implications
por: Kwok, Cecilia, et al.
Publicado: (2023)

Randomised controlled trial protocol for the PROTECT-CS Study: PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery
por: Rose, Alexandra V, et al.
Publicado: (2021)

Pre-clinical Evidence: Berberine as a Promising Cardioprotective Candidate for Myocardial Ischemia/Reperfusion Injury, a Systematic Review, and Meta-Analysis
por: Chen, Cong, et al.
Publicado: (2021)

Comparative analysis of right ventricular metabolic reprogramming in pre-clinical rat models of severe pulmonary hypertension-induced right ventricular failure
por: Banerjee, Somanshu, et al.
Publicado: (2022)

Cardiac Magnetic Resonance in Rheumatology to Detect Cardiac Involvement Since Early and Pre-clinical Stages of the Autoimmune Diseases: A Narrative Review
por: Sierra-Galan, Lilia M., et al.
Publicado: (2022)

Comparison of Drug-Coated Balloon Angioplasty vs. Drug-Eluting Stent Implantation for Drug-Eluting Stent Restenosis in the Routine Clinical Practice: A Meta-Analysis of Randomized Controlled Trials
por: Zhu, Yong, et al.
Publicado: (2021)

In vitro and in vivo Assessment of Keratose as a Novel Excipient of Paclitaxel Coated Balloons
por: Turner, Emily, et al.
Publicado: (2018)

Analysis of Clinical Features of Non-steroidal Anti-inflammatory Drugs Induced Kounis Syndrome
por: Wang, Chunjiang, et al.
Publicado: (2022)

Prevalence and Prognostic Significance of Frailty in Gerontal Inpatients With Pre-clinical Heart Failure: A Subgroup Analysis of a Prospective Observational Cohort Study in China
por: Zheng, Pei-Pei, et al.
Publicado: (2020)

PATHway I: design and rationale for the investigation of the feasibility, clinical effectiveness and cost-effectiveness of a technology-enabled cardiac rehabilitation platform
por: Claes, Jomme, et al.
Publicado: (2017)

Emerging Challenges of Radiation-Associated Cardiovascular Dysfunction (RACVD) in Modern Radiation Oncology: Clinical Practice, Bench Investigation, and Multidisciplinary Care
por: Lee, Moon-Sing, et al.
Publicado: (2020)

Plasma Metabolomics of Acute Coronary Syndrome Patients Based on Untargeted Liquid Chromatography–Mass Spectrometry
por: Zhong, Wei, et al.
Publicado: (2021)

Pre-operative Considerations in Adult Mucopolysaccharidosis Patients Planned for Cardiac Intervention
por: Cross, Benjamin, et al.
Publicado: (2022)

The prognostic value of pre-operative coronary evaluation in kidney transplanted patients
por: Steinmetz, Tali, et al.
Publicado: (2022)

Cardiovascular drug interventions in the cardio-oncology clinic by a cardiology pharmacist: ICOP-Pharm study
por: Yaseen, Israa Fadhil, et al.
Publicado: (2022)

Bifurcation strategies using second-generation drug-eluting stents on clinical outcomes in diabetic patients
por: Cha, Jung-Joon, et al.
Publicado: (2022)

New Delivery Systems of Stem Cells for Vascular Regeneration in Ischemia
por: Fakoya, Adegbenro Omotuyi John
Publicado: (2017)

Investigation Into the Risk Factors Related to In-stent Restenosis in Elderly Patients With Coronary Heart Disease and Type 2 Diabetes Within 2 Years After the First Drug-Eluting Stent Implantation
por: Yi, Ming, et al.
Publicado: (2022)

Pre-infarction Angina: Time Interval to Onset of Myocardial Infarction and Comorbidity Predictors
por: Sotomi, Yohei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e0148emiml2amq47dpd0635jv9