Cargando…

Esophagitis Dissecans Superficialis: A Case Report

Esophagitis dissecans superficialis (EDS) is a rare esophageal lesion characterized by sloughing of the esophageal mucosa. Typically asymptomatic and histopathologically nonspecific, diagnosis relies on endoscopic appearance. We report a case of an 81-year-old female who presented with an 8-pound we...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaher, Eli A, Patel, Parth, Zaher, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540652/
https://www.ncbi.nlm.nih.gov/pubmed/37779763
http://dx.doi.org/10.7759/cureus.44372
_version_ 1785113755380613120
author Zaher, Eli A
Patel, Parth
Zaher, Daria
author_facet Zaher, Eli A
Patel, Parth
Zaher, Daria
author_sort Zaher, Eli A
collection PubMed
description Esophagitis dissecans superficialis (EDS) is a rare esophageal lesion characterized by sloughing of the esophageal mucosa. Typically asymptomatic and histopathologically nonspecific, diagnosis relies on endoscopic appearance. We report a case of an 81-year-old female who presented with an 8-pound weight loss in two weeks. Upper endoscopy showed severe mucosal changes with sloughing in the lower esophagus, consistent with EDS. Histopathology confirmed the diagnosis. No offending agents were identified, and high-dose proton pump inhibitors (PPIs) were initiated, resulting in symptom improvement. EDS remains poorly understood; it is associated with medication use, esophageal motility disorders, and autoimmune conditions. EDS should be considered in unexplained weight loss cases, with treatment focused on the discontinuation of culprits and PPI therapy.
format Online
Article
Text
id pubmed-10540652
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-105406522023-09-30 Esophagitis Dissecans Superficialis: A Case Report Zaher, Eli A Patel, Parth Zaher, Daria Cureus Internal Medicine Esophagitis dissecans superficialis (EDS) is a rare esophageal lesion characterized by sloughing of the esophageal mucosa. Typically asymptomatic and histopathologically nonspecific, diagnosis relies on endoscopic appearance. We report a case of an 81-year-old female who presented with an 8-pound weight loss in two weeks. Upper endoscopy showed severe mucosal changes with sloughing in the lower esophagus, consistent with EDS. Histopathology confirmed the diagnosis. No offending agents were identified, and high-dose proton pump inhibitors (PPIs) were initiated, resulting in symptom improvement. EDS remains poorly understood; it is associated with medication use, esophageal motility disorders, and autoimmune conditions. EDS should be considered in unexplained weight loss cases, with treatment focused on the discontinuation of culprits and PPI therapy. Cureus 2023-08-30 /pmc/articles/PMC10540652/ /pubmed/37779763 http://dx.doi.org/10.7759/cureus.44372 Text en Copyright © 2023, Zaher et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Zaher, Eli A
Patel, Parth
Zaher, Daria
Esophagitis Dissecans Superficialis: A Case Report
title Esophagitis Dissecans Superficialis: A Case Report
title_full Esophagitis Dissecans Superficialis: A Case Report
title_fullStr Esophagitis Dissecans Superficialis: A Case Report
title_full_unstemmed Esophagitis Dissecans Superficialis: A Case Report
title_short Esophagitis Dissecans Superficialis: A Case Report
title_sort esophagitis dissecans superficialis: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540652/
https://www.ncbi.nlm.nih.gov/pubmed/37779763
http://dx.doi.org/10.7759/cureus.44372
work_keys_str_mv AT zaherelia esophagitisdissecanssuperficialisacasereport
AT patelparth esophagitisdissecanssuperficialisacasereport
AT zaherdaria esophagitisdissecanssuperficialisacasereport