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Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia

BACKGROUND: COVID-19 is a virulent viral infection by SARS-CoV-2 which caused pandemic and high mortality. One of the numerous risk factors for worse clinical outcomes in COVID-19 patients is the presence of comorbidity. Diabetes Mellitus is a chronic metabolic disease frequently in COVID-19 patient...

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Autores principales: Marpaung, Nadya Joana, Lubis, Mustafa Ali Azmi, Amelia, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540745/
https://www.ncbi.nlm.nih.gov/pubmed/37781495
http://dx.doi.org/10.5455/aim.2023.31.182-185
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author Marpaung, Nadya Joana
Lubis, Mustafa Ali Azmi
Amelia, Rina
author_facet Marpaung, Nadya Joana
Lubis, Mustafa Ali Azmi
Amelia, Rina
author_sort Marpaung, Nadya Joana
collection PubMed
description BACKGROUND: COVID-19 is a virulent viral infection by SARS-CoV-2 which caused pandemic and high mortality. One of the numerous risk factors for worse clinical outcomes in COVID-19 patients is the presence of comorbidity. Diabetes Mellitus is a chronic metabolic disease frequently in COVID-19 patients. Insulin resistance, causes chronic inflammation in the body, may aggravate the clinical outcome COVID-19 patients. OBJECTIVE: The aim of the study was to examine factors that impact clinical outcomes in COVID-19 T2DM patients. METHODS: The method used an analytical method with cross sectional design. Population is inpatients in Haji Adam Malik Hospital diagnosed with COVID-19 and Diabetes Mellitus Type 2 with 99 inpatients as sample. The data used are secondary data obtained through medical records from a hospital covering patients characteristics and laboratory result The data was analyzed using t-independent and chi square test with SPSS program. RESULTS: Clinical outcomes for 99 patients are 60 patients are cured and 39 patients are dead. analytical study found a significant correlation between factors impacting clinical outcomes on COVID-19 patients with T2DM that are HbA1c level, D-dimer, cholesterol total and COVID-19 degree of severity and the clinical outcomes (p<0,05). CONCLUSION: HbA1c level, D-dimer, total cholesterol and the infection degree of severity affects the clinical outcomes on COVID-19 with T2DM (p<0,05).
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spelling pubmed-105407452023-09-30 Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia Marpaung, Nadya Joana Lubis, Mustafa Ali Azmi Amelia, Rina Acta Inform Med Original Paper BACKGROUND: COVID-19 is a virulent viral infection by SARS-CoV-2 which caused pandemic and high mortality. One of the numerous risk factors for worse clinical outcomes in COVID-19 patients is the presence of comorbidity. Diabetes Mellitus is a chronic metabolic disease frequently in COVID-19 patients. Insulin resistance, causes chronic inflammation in the body, may aggravate the clinical outcome COVID-19 patients. OBJECTIVE: The aim of the study was to examine factors that impact clinical outcomes in COVID-19 T2DM patients. METHODS: The method used an analytical method with cross sectional design. Population is inpatients in Haji Adam Malik Hospital diagnosed with COVID-19 and Diabetes Mellitus Type 2 with 99 inpatients as sample. The data used are secondary data obtained through medical records from a hospital covering patients characteristics and laboratory result The data was analyzed using t-independent and chi square test with SPSS program. RESULTS: Clinical outcomes for 99 patients are 60 patients are cured and 39 patients are dead. analytical study found a significant correlation between factors impacting clinical outcomes on COVID-19 patients with T2DM that are HbA1c level, D-dimer, cholesterol total and COVID-19 degree of severity and the clinical outcomes (p<0,05). CONCLUSION: HbA1c level, D-dimer, total cholesterol and the infection degree of severity affects the clinical outcomes on COVID-19 with T2DM (p<0,05). Academy of Medical sciences 2023 /pmc/articles/PMC10540745/ /pubmed/37781495 http://dx.doi.org/10.5455/aim.2023.31.182-185 Text en © 2023 Nadya Joana Marpaung, Mustafa Ali Azmi Lubis, Rina Amelia https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Marpaung, Nadya Joana
Lubis, Mustafa Ali Azmi
Amelia, Rina
Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title_full Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title_fullStr Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title_full_unstemmed Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title_short Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia
title_sort factors affecting the outcomes of covid-19 in diabetes patients at haji adam malik general hospital medan, indonesia
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540745/
https://www.ncbi.nlm.nih.gov/pubmed/37781495
http://dx.doi.org/10.5455/aim.2023.31.182-185
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