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A pilot study: Nano‐hydroxyapatite‐PEG/PLA containing low dose rhBMP2 stimulates proliferation and osteogenic differentiation of human bone marrow derived mesenchymal stem cells

BACKGROUND: Bone morphogenetic protein 2 (BMP2) can enhance posterolateral spinal fusion (PLSF). The minimum effective dose that may stimulate mesenchymal stem cells however remains unknown. Nano‐hydroxyapatite (nHAp) polyethylene glycol (PEG)/polylactic acid (PLA) was combined with recombinant huma...

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Detalles Bibliográficos
Autores principales: Dede, Eda Çiftci, Gizer, Merve, Korkusuz, Feza, Bal, Zeynep, Ishiguro, Hiroyuki, Yoshikawa, Hideki, Kaito, Takashi, Korkusuz, Petek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540822/
https://www.ncbi.nlm.nih.gov/pubmed/37780828
http://dx.doi.org/10.1002/jsp2.1258

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