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In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage

STUDY DESIGN: In vitro biomechanical study investigating the coupled motions of the whole normative human thoracic spine (TS) and lumbar spine (LS) with rib cage. OBJECTIVE: To quantify the region‐specific coupled motion patterns and magnitudes of the TS, thoracolumbar junction (TLJ), and LS simulta...

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Autores principales: Orbach, Mattan R., Mahoney, Jonathan, Bucklen, Brandon S., Balasubramanian, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540827/
https://www.ncbi.nlm.nih.gov/pubmed/37780824
http://dx.doi.org/10.1002/jsp2.1257
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author Orbach, Mattan R.
Mahoney, Jonathan
Bucklen, Brandon S.
Balasubramanian, Sriram
author_facet Orbach, Mattan R.
Mahoney, Jonathan
Bucklen, Brandon S.
Balasubramanian, Sriram
author_sort Orbach, Mattan R.
collection PubMed
description STUDY DESIGN: In vitro biomechanical study investigating the coupled motions of the whole normative human thoracic spine (TS) and lumbar spine (LS) with rib cage. OBJECTIVE: To quantify the region‐specific coupled motion patterns and magnitudes of the TS, thoracolumbar junction (TLJ), and LS simultaneously. BACKGROUND: Studying spinal coupled motions is important in understanding the development of complex spinal deformities and providing data for validating computational models. However, coupled motion patterns reported in vitro are controversial, and no quantitative data on region‐specific coupled motions of the whole human TS and LS are available. METHODS: Pure, unconstrained bending moments of 8 Nm were applied to seven fresh‐frozen human cadaveric TS and LS specimens (mean age: 70.3 ± 11.3 years) with rib cages to elicit flexion‐extension (FE), lateral bending (LB), and axial rotation (AR). During each primary motion, region‐specific rotational range of motion (ROM) data were captured. RESULTS: No statistically significant, consistent coupled motion patterns were observed during primary FE. During primary LB, there was significant (p < 0.05) ipsilateral AR in the TS and a general pattern of contralateral coupled AR in the TLJ and LS. There was also a tendency for the TS to extend and the LS to flex. During primary AR, significant coupled LB was ipsilateral in the TS and contralateral in both the TLJ and LS. Significant coupled flexion in the LS was also observed. Coupled LB and AR ROMs were not significantly different between the TS and LS or from one another. CONCLUSIONS: The findings support evidence of consistent coupled motion patterns of the TS and LS during LB and AR. These novel data may serve as reference for computational model validations and future in vitro studies investigating spinal deformities and implants.
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spelling pubmed-105408272023-09-30 In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage Orbach, Mattan R. Mahoney, Jonathan Bucklen, Brandon S. Balasubramanian, Sriram JOR Spine Research Articles STUDY DESIGN: In vitro biomechanical study investigating the coupled motions of the whole normative human thoracic spine (TS) and lumbar spine (LS) with rib cage. OBJECTIVE: To quantify the region‐specific coupled motion patterns and magnitudes of the TS, thoracolumbar junction (TLJ), and LS simultaneously. BACKGROUND: Studying spinal coupled motions is important in understanding the development of complex spinal deformities and providing data for validating computational models. However, coupled motion patterns reported in vitro are controversial, and no quantitative data on region‐specific coupled motions of the whole human TS and LS are available. METHODS: Pure, unconstrained bending moments of 8 Nm were applied to seven fresh‐frozen human cadaveric TS and LS specimens (mean age: 70.3 ± 11.3 years) with rib cages to elicit flexion‐extension (FE), lateral bending (LB), and axial rotation (AR). During each primary motion, region‐specific rotational range of motion (ROM) data were captured. RESULTS: No statistically significant, consistent coupled motion patterns were observed during primary FE. During primary LB, there was significant (p < 0.05) ipsilateral AR in the TS and a general pattern of contralateral coupled AR in the TLJ and LS. There was also a tendency for the TS to extend and the LS to flex. During primary AR, significant coupled LB was ipsilateral in the TS and contralateral in both the TLJ and LS. Significant coupled flexion in the LS was also observed. Coupled LB and AR ROMs were not significantly different between the TS and LS or from one another. CONCLUSIONS: The findings support evidence of consistent coupled motion patterns of the TS and LS during LB and AR. These novel data may serve as reference for computational model validations and future in vitro studies investigating spinal deformities and implants. John Wiley & Sons, Inc. 2023-05-04 /pmc/articles/PMC10540827/ /pubmed/37780824 http://dx.doi.org/10.1002/jsp2.1257 Text en © 2023 The Authors. JOR Spine published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Orbach, Mattan R.
Mahoney, Jonathan
Bucklen, Brandon S.
Balasubramanian, Sriram
In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title_full In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title_fullStr In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title_full_unstemmed In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title_short In vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
title_sort in vitro coupled motions of the whole human thoracic and lumbar spine with rib cage
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540827/
https://www.ncbi.nlm.nih.gov/pubmed/37780824
http://dx.doi.org/10.1002/jsp2.1257
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