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Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer orga...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540838/ https://www.ncbi.nlm.nih.gov/pubmed/37781203 http://dx.doi.org/10.3389/fonc.2023.1253573 |
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author | Tan, Shunshun Deng, Jiali Deng, Haobin Lu, Lijun Qin, Zhenzhe Liu, Yu Tang, Lifeng Li, Zhonghua |
author_facet | Tan, Shunshun Deng, Jiali Deng, Haobin Lu, Lijun Qin, Zhenzhe Liu, Yu Tang, Lifeng Li, Zhonghua |
author_sort | Tan, Shunshun |
collection | PubMed |
description | OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer organoids. METHODS: A total of 3189 publications on organoids in cancer research from 1991 to 2021 were collected from the Science Citation Index-Expanded (SCIE) of Web of Science (WoS). Bibliometric methods such as the R package “Bibliometrix,” Citespace, and VOS viewer software were employed to investigate and visualize bibliographic coupling, co-citation, co-authorship, and co-occurrence trends, as well as publication trends in the field of organoids in cancer research. RESULTS: From 1991 to 2021, there has been a significant increase in publications on cancer organoids, with most articles being from North America, Eastern Asia, and Western Europe. The USA had the highest number of publications, citations, prolific authors, and research funding globally. Cancers was the journal with the most publications, while Nature had the best total link strength. Harvard University were the most contributive institutions. The global research in this field could be classified into five clusters: chemotherapy study, organoids for drug screening, different models, molecular mechanism study, and organoid construction. These areas are expected to remain hotspots for future research. CONCLUSIONS: The number of publications on organoids in cancer research is expected to increase based on current global trends. |
format | Online Article Text |
id | pubmed-10540838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105408382023-09-30 Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 Tan, Shunshun Deng, Jiali Deng, Haobin Lu, Lijun Qin, Zhenzhe Liu, Yu Tang, Lifeng Li, Zhonghua Front Oncol Oncology OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer organoids. METHODS: A total of 3189 publications on organoids in cancer research from 1991 to 2021 were collected from the Science Citation Index-Expanded (SCIE) of Web of Science (WoS). Bibliometric methods such as the R package “Bibliometrix,” Citespace, and VOS viewer software were employed to investigate and visualize bibliographic coupling, co-citation, co-authorship, and co-occurrence trends, as well as publication trends in the field of organoids in cancer research. RESULTS: From 1991 to 2021, there has been a significant increase in publications on cancer organoids, with most articles being from North America, Eastern Asia, and Western Europe. The USA had the highest number of publications, citations, prolific authors, and research funding globally. Cancers was the journal with the most publications, while Nature had the best total link strength. Harvard University were the most contributive institutions. The global research in this field could be classified into five clusters: chemotherapy study, organoids for drug screening, different models, molecular mechanism study, and organoid construction. These areas are expected to remain hotspots for future research. CONCLUSIONS: The number of publications on organoids in cancer research is expected to increase based on current global trends. Frontiers Media S.A. 2023-09-15 /pmc/articles/PMC10540838/ /pubmed/37781203 http://dx.doi.org/10.3389/fonc.2023.1253573 Text en Copyright © 2023 Tan, Deng, Deng, Lu, Qin, Liu, Tang and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Tan, Shunshun Deng, Jiali Deng, Haobin Lu, Lijun Qin, Zhenzhe Liu, Yu Tang, Lifeng Li, Zhonghua Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title | Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title_full | Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title_fullStr | Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title_full_unstemmed | Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title_short | Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
title_sort | global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540838/ https://www.ncbi.nlm.nih.gov/pubmed/37781203 http://dx.doi.org/10.3389/fonc.2023.1253573 |
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