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Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021

OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer orga...

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Autores principales: Tan, Shunshun, Deng, Jiali, Deng, Haobin, Lu, Lijun, Qin, Zhenzhe, Liu, Yu, Tang, Lifeng, Li, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540838/
https://www.ncbi.nlm.nih.gov/pubmed/37781203
http://dx.doi.org/10.3389/fonc.2023.1253573
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author Tan, Shunshun
Deng, Jiali
Deng, Haobin
Lu, Lijun
Qin, Zhenzhe
Liu, Yu
Tang, Lifeng
Li, Zhonghua
author_facet Tan, Shunshun
Deng, Jiali
Deng, Haobin
Lu, Lijun
Qin, Zhenzhe
Liu, Yu
Tang, Lifeng
Li, Zhonghua
author_sort Tan, Shunshun
collection PubMed
description OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer organoids. METHODS: A total of 3189 publications on organoids in cancer research from 1991 to 2021 were collected from the Science Citation Index-Expanded (SCIE) of Web of Science (WoS). Bibliometric methods such as the R package “Bibliometrix,” Citespace, and VOS viewer software were employed to investigate and visualize bibliographic coupling, co-citation, co-authorship, and co-occurrence trends, as well as publication trends in the field of organoids in cancer research. RESULTS: From 1991 to 2021, there has been a significant increase in publications on cancer organoids, with most articles being from North America, Eastern Asia, and Western Europe. The USA had the highest number of publications, citations, prolific authors, and research funding globally. Cancers was the journal with the most publications, while Nature had the best total link strength. Harvard University were the most contributive institutions. The global research in this field could be classified into five clusters: chemotherapy study, organoids for drug screening, different models, molecular mechanism study, and organoid construction. These areas are expected to remain hotspots for future research. CONCLUSIONS: The number of publications on organoids in cancer research is expected to increase based on current global trends.
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spelling pubmed-105408382023-09-30 Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021 Tan, Shunshun Deng, Jiali Deng, Haobin Lu, Lijun Qin, Zhenzhe Liu, Yu Tang, Lifeng Li, Zhonghua Front Oncol Oncology OBJECTIVE: In the last three decades, there has been a surge in research on cancer organoids using 3D culture technologies, which has resulted in the development of physiological human cancer models. This study aims to provide an overview of the global trends and frontiers in research on cancer organoids. METHODS: A total of 3189 publications on organoids in cancer research from 1991 to 2021 were collected from the Science Citation Index-Expanded (SCIE) of Web of Science (WoS). Bibliometric methods such as the R package “Bibliometrix,” Citespace, and VOS viewer software were employed to investigate and visualize bibliographic coupling, co-citation, co-authorship, and co-occurrence trends, as well as publication trends in the field of organoids in cancer research. RESULTS: From 1991 to 2021, there has been a significant increase in publications on cancer organoids, with most articles being from North America, Eastern Asia, and Western Europe. The USA had the highest number of publications, citations, prolific authors, and research funding globally. Cancers was the journal with the most publications, while Nature had the best total link strength. Harvard University were the most contributive institutions. The global research in this field could be classified into five clusters: chemotherapy study, organoids for drug screening, different models, molecular mechanism study, and organoid construction. These areas are expected to remain hotspots for future research. CONCLUSIONS: The number of publications on organoids in cancer research is expected to increase based on current global trends. Frontiers Media S.A. 2023-09-15 /pmc/articles/PMC10540838/ /pubmed/37781203 http://dx.doi.org/10.3389/fonc.2023.1253573 Text en Copyright © 2023 Tan, Deng, Deng, Lu, Qin, Liu, Tang and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Tan, Shunshun
Deng, Jiali
Deng, Haobin
Lu, Lijun
Qin, Zhenzhe
Liu, Yu
Tang, Lifeng
Li, Zhonghua
Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title_full Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title_fullStr Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title_full_unstemmed Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title_short Global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
title_sort global cluster analysis and network visualization in organoids in cancer research: a scientometric mapping from 1991 to 2021
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540838/
https://www.ncbi.nlm.nih.gov/pubmed/37781203
http://dx.doi.org/10.3389/fonc.2023.1253573
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