Cargando…

Secreted aspartyl protease 3 regulated by the Ras/cAMP/PKA pathway promotes the virulence of Candida auris

The surge of multidrug-resistant fungal pathogens, especially Candida auris, poses significant threats to global public health. Candida auris exhibits resistance to multiple antifungal drugs, leading to major outbreaks and a high mortality rate. With an urgent call for innovative therapeutic strateg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji-Seok, Lee, Kyung-Tae, Bahn, Yong-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540861/ https://www.ncbi.nlm.nih.gov/pubmed/37780854 http://dx.doi.org/10.3389/fcimb.2023.1257897

Ejemplares similares

Mannich base limits Candida albicans virulence by inactivating Ras-cAMP-PKA pathway
por: Rajasekharan, Satish Kumar, et al.
Publicado: (2018)

Deciphering the regulatory mechanisms of the cAMP/protein kinase A pathway and their roles in the pathogenicity of Candida auris
por: Kim, Ji-Seok, et al.
Publicado: (2023)

Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
por: Poh, Si En, et al.
Publicado: (2020)

Functional Characterization of Secreted Aspartyl Proteases in Candida parapsilosis
por: Singh, Dhirendra Kumar, et al.
Publicado: (2019)

Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans
por: Silao, Fitz Gerald S., et al.
Publicado: (2019)

Editorial: Candida auris - understanding the new superbug
por: Banik, Sukalyani
Publicado: (2023)

Photodynamic Therapy Is Effective Against Candida auris Biofilms
por: Bapat, Priyanka S., et al.
Publicado: (2021)

Transcriptome Signatures Predict Phenotypic Variations of Candida auris
por: Jenull, Sabrina, et al.
Publicado: (2021)

The cAMP/Protein Kinase A Pathway Regulates Virulence and Adaptation to Host Conditions in Cryptococcus neoformans
por: Caza, Mélissa, et al.
Publicado: (2019)

Secretion of the siderophore rhizoferrin is regulated by the cAMP-PKA pathway and is involved in the virulence of Mucor lusitanicus
por: Alejandre-Castañeda, Viridiana, et al.
Publicado: (2022)

Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in Trypanosoma brucei
por: Bachmaier, Sabine, et al.
Publicado: (2023)

The Postbiotic Activity of Lactobacillus paracasei 28.4 Against Candida auris
por: Rossoni, Rodnei Dennis, et al.
Publicado: (2020)

Application of Machine Learning Classifier to Candida auris Drug Resistance Analysis
por: Li, Dingchen, et al.
Publicado: (2021)

Candida albicans Filamentation Does Not Require the cAMP-PKA Pathway In Vivo
por: Wakade, Rohan S., et al.
Publicado: (2022)

Conserved and Divergent Functions of the cAMP/PKA Signaling Pathway in Candida albicans and Candida tropicalis
por: Lin, Chi-Jan, et al.
Publicado: (2018)

Screening the CALIBR ReFRAME Library in Search for Inhibitors of Candida auris Biofilm Formation
por: Wall, Gina, et al.
Publicado: (2020)

Colonized patients by Candida auris: Third and largest outbreak in Brazil and impact of biofilm formation
por: de Melo, Camylla Carvalho, et al.
Publicado: (2023)

Candida auris Identification and Rapid Antifungal Susceptibility Testing Against Echinocandins by MALDI-TOF MS
por: Vatanshenassan, Mansoureh, et al.
Publicado: (2019)

Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen Candida auris
por: de Oliveira, Haroldo Cesar, et al.
Publicado: (2019)

The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae
por: Besozzi, Daniela, et al.
Publicado: (2012)

The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans
por: Hnisz, Denes, et al.
Publicado: (2010)

PKA compartmentalization links cAMP signaling and autophagy
por: Grisan, Francesca, et al.
Publicado: (2021)

Regulation of Cardiac PKA Signaling by cAMP and Oxidants
por: Cuello, Friederike, et al.
Publicado: (2021)

Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy
por: Yu, Qi, et al.
Publicado: (2022)

Effect of cAMP Receptor Protein Gene on Growth Characteristics and Stress Resistance of Haemophilus parasuis Serovar 5
por: Jiang, Changsheng, et al.
Publicado: (2020)

Role of the cAMP signaling pathway in the dissemination and development on pepper fruit anthracnose disease caused by Colletotrichum scovillei
por: Fu, Teng, et al.
Publicado: (2022)

Are We Ready for Nosocomial Candida auris Infections? Rapid Identification and Antifungal Resistance Detection Using MALDI-TOF Mass Spectrometry May Be the Answer
por: De Carolis, Elena, et al.
Publicado: (2021)

The yapsin family of aspartyl proteases regulate glucose homeostasis in Candida glabrata
por: Askari, Fizza, et al.
Publicado: (2022)

Regulation of Nuclear PKA revealed by spatiotemporal manipulation of cAMP
por: Sample, Vedangi, et al.
Publicado: (2012)

Complex roles of cAMP–PKA–CREB signaling in cancer
por: Zhang, Hongying, et al.
Publicado: (2020)

Cardiac cAMP-PKA Signaling Compartmentalization in Myocardial Infarction
por: Colombe, Anne-Sophie, et al.
Publicado: (2021)

cAMP/PKA Signaling Modulates Mitochondrial Supercomplex Organization
por: Signorile, Anna, et al.
Publicado: (2022)

cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2022)

Role of peptidoglycan recycling enzymes AmpD and AnmK in Acinetobacter baumannii virulence features
por: Tajuelo, Ana, et al.
Publicado: (2023)

Astrocytic Calcium and cAMP in Neurodegenerative Diseases
por: Sobolczyk, Marta, et al.
Publicado: (2022)

Activation of PKA in cell requires higher concentration of cAMP than in vitro: implications for compartmentalization of cAMP signalling
por: Koschinski, Andreas, et al.
Publicado: (2017)

Aspartyl proteases in Candida glabrata are required for suppression of the host innate immune response
por: Rasheed, Mubashshir, et al.
Publicado: (2018)

Entamoeba histolytica Cyclooxygenase-Like Protein Regulates Cysteine Protease Expression and Virulence
por: Shahi, Preeti, et al.
Publicado: (2019)

Update on the Pathogenesis, Virulence, and Treatment of Candida auris
por: Watkins, Richard R., et al.
Publicado: (2022)

Signaling Diversity of PKA Achieved Via a Ca(2+)-cAMP-PKA Oscillatory Circuit
por: Ni, Qiang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tksj63ope27578t60gsto3933m