Cargando…

Association detection between multiple traits and rare variants based on family data via a nonparametric method

BACKGROUND: The rapid development of next-generation sequencing technologies allow people to analyze human complex diseases at the molecular level. It has been shown that rare variants play important roles for human diseases besides common variants. Thus, effective statistical methods need to be pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chi, Jinling, Xu, Meijuan, Sheng, Xiaona, Zhou, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541022/ https://www.ncbi.nlm.nih.gov/pubmed/37780393 http://dx.doi.org/10.7717/peerj.16040

Ejemplares similares

Utilizing mutual information for detecting rare and common variants associated with a categorical trait
por: Sun, Leiming, et al.
Publicado: (2016)

NOBIAS: Analyzing Anomalous Diffusion in Single-Molecule Tracks With Nonparametric Bayesian Inference
por: Chen, Ziyuan, et al.
Publicado: (2021)

Quantitative trait locus mapping analysis of multiple traits when using genotype data with potential errors
por: Tong, Liang, et al.
Publicado: (2021)

Performance of methods for SARS-CoV-2 variant detection and abundance estimation within mixed population samples
por: Kayikcioglu, Tunc, et al.
Publicado: (2023)

Obesity associated with a novel mitochondrial tRNA(Cys) 5802A>G mutation in a Chinese family
por: Wang, Jinling, et al.
Publicado: (2020)

Evaluation of performance of leading algorithms for variant pathogenicity predictions and designing a combinatory predictor method: application to Rett syndrome variants
por: Ganakammal, Satishkumar Ranganathan, et al.
Publicado: (2019)

microTrait: A Toolset for a Trait-Based Representation of Microbial Genomes
por: Karaoz, Ulas, et al.
Publicado: (2022)

Early detection of emerging SARS-CoV-2 variants of interest for experimental evaluation
por: Wallace, Zachary S., et al.
Publicado: (2022)

Modeling transcriptional activation changes to Gal4 variants via structure-based computational mutagenesis
por: Masso, Majid, et al.
Publicado: (2018)

Expression profiles and prognostic significance of WNT family members in glioma via bioinformatic analysis
por: Xu, Anqi, et al.
Publicado: (2020)

Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?
por: Smith, Thomas C.A., et al.
Publicado: (2016)

GROM-RD: resolving genomic biases to improve read depth detection of copy number variants
por: Smith, Sean D., et al.
Publicado: (2015)

DiscoSnp-RAD: de novo detection of small variants for RAD-Seq population genomics
por: Gauthier, Jérémy, et al.
Publicado: (2020)

Identifying multiple collagen gene family members as potential gastric cancer biomarkers using integrated bioinformatics analysis
por: Li, Zhaoxing, et al.
Publicado: (2020)

DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations
por: Andrews, T. Daniel, et al.
Publicado: (2016)

Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach
por: Ding, Lili, et al.
Publicado: (2011)

sv-callers: a highly portable parallel workflow for structural variant detection in whole-genome sequence data
por: Kuzniar, Arnold, et al.
Publicado: (2020)

Comprehensive analysis of inhibitor of differentiation/DNA-binding gene family in lung cancer using bioinformatics methods
por: Xu, Suming, et al.
Publicado: (2020)

DNMT family induces down-regulation of NDRG1 via DNA methylation and clinicopathological significance in gastric cancer
por: Chang, Xiaojing, et al.
Publicado: (2021)

Identification of core genes associated with prostate cancer progression and outcome via bioinformatics analysis in multiple databases
por: Wang, Yutao, et al.
Publicado: (2020)

An effective and comprehensible method to detect and evaluate retinal damage due to diabetes complications
por: Dao, Quang Toan, et al.
Publicado: (2023)

ksrMKL: a novel method for identification of kinase–substrate relationships using multiple kernel learning
por: Wang, Minghui, et al.
Publicado: (2017)

Prognostic value of the S100 calcium-binding protein family members in hepatocellular carcinoma
por: Wei, Ran, et al.
Publicado: (2023)

cRegions—a tool for detecting conserved cis-elements in multiple sequence alignment of diverged coding sequences
por: Puustusmaa, Mikk, et al.
Publicado: (2019)

Upregulation of desmoglein 2 and its clinical value in lung adenocarcinoma: a comprehensive analysis by multiple bioinformatics methods
por: Sun, Ruiying, et al.
Publicado: (2020)

GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
por: Mao, Yafei
Publicado: (2019)

Detection of subtype-specific breast cancer surface protein biomarkers via a novel transcriptomics approach
por: Mercatelli, Daniele, et al.
Publicado: (2021)

Feature selection based on differentially correlated gene pairs reveals the mechanism of IFN-β therapy for multiple sclerosis
por: Jin, Tao, et al.
Publicado: (2020)

Inflammatory bowel disease biomarkers of human gut microbiota selected via different feature selection methods
por: Bakir-Gungor, Burcu, et al.
Publicado: (2022)

Orthogonal analysis of variants in APOE gene using in-silico approaches reveals novel disrupting variants
por: Li, Chang, et al.
Publicado: (2023)

SC-JNMF: single-cell clustering integrating multiple quantification methods based on joint non-negative matrix factorization
por: Shiga, Mikio, et al.
Publicado: (2021)

Correlations between glycolysis with clinical traits and immune function in bladder urothelial carcinoma
por: Che, Kai, et al.
Publicado: (2021)

A variable-rate quantitative trait evolution model using penalized-likelihood
por: Revell, Liam J.
Publicado: (2021)

Feature screening for survival trait with application to TCGA high-dimensional genomic data
por: Wang, Jie-Huei, et al.
Publicado: (2022)

Variant profiling of evolving prokaryotic populations
por: Zojer, Markus, et al.
Publicado: (2017)

Weighted gene correlation network analysis reveals novel regulatory modules associated with recurrent early pregnancy loss
por: Li, Xiaoxiao, et al.
Publicado: (2020)

Pathways of topological rank analysis (PoTRA): a novel method to detect pathways involved in hepatocellular carcinoma
por: Li, Chaoxing, et al.
Publicado: (2018)

VirHunter: A Deep Learning-Based Method for Detection of Novel RNA Viruses in Plant Sequencing Data
por: Sukhorukov, Grigorii, et al.
Publicado: (2022)

miR2Trait: an integrated resource for investigating miRNA-disease associations
por: Babu, Poornima, et al.
Publicado: (2022)

Evolution of sequence traits of prion-like proteins linked to amyotrophic lateral sclerosis (ALS)
por: Luo, Jiayi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_th0716o7tpuq5au1lnkvf44odb