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Predicting gene expression changes upon epigenomic drug treatment
BACKGROUND: Tumors are characterized by global changes in epigenetic changes such as DNA methylation and histone modifications that are functionally linked to tumor progression. Accordingly, several drugs targeting the epigenome have been proposed for cancer therapy, notably, histone deacetylase inh...
Autores principales: | Agrawal, Piyush, Gopalan, Vishaka, Hannenhalli, Sridhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541107/ https://www.ncbi.nlm.nih.gov/pubmed/37781626 http://dx.doi.org/10.1101/2023.07.20.549955 |
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