Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging

Demyelination occurs in aging and associated diseases, including Alzheimer’s disease. Several of these diseases exhibit sex differences in prevalence and severity. Biological sex primarily stems from sex chromosomes and gonads releasing sex hormones. To dissect mechanisms underlying sex differences...

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Detalles Bibliográficos
Autores principales: Lopez-Lee, Chloe, Kodama, Lay, Fan, Li, Wong, Man Ying, Foxe, Nessa R., Jiaz, Laraib, Yu, Fangmin, Ye, Pearly, Zhu, Jingjie, Norman, Kendra, Torres, Eileen Ruth, Kim, Rachel D., Mousa, Gergey Alzaem, Dubal, Dena, Liddelow, Shane, Luo, Wenjie, Gan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541118/
https://www.ncbi.nlm.nih.gov/pubmed/37781600
http://dx.doi.org/10.1101/2023.09.19.558439

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