Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity

The comprehensive assessment of long-term effects of reducing intake of energy (CALERIE-II; NCT00427193) clinical trial established that caloric restriction (CR) in humans lowers inflammation. The identity and mechanism of endogenous CR-mimetics that can be deployed to control obesity-associated inf...

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Detalles Bibliográficos
Autores principales: Ryu, Seungjin, Spadaro, Olga, Sidorov, Sviatoslav, Lee, Aileen H., Caprio, Sonia, Morrison, Christopher, Smith, Steven R., Ravussin, Eric, Shchukina, Irina, Artyomov, Maxim N., Youm, Yun-Hee, Dixit, Vishwa Deep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541189/
https://www.ncbi.nlm.nih.gov/pubmed/37781916
http://dx.doi.org/10.1172/JCI169173

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