NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer

Colorectal cancer (CRC) at advanced stages is rarely curable, underscoring the importance of exploring the mechanism of CRC progression and invasion. NOD-like receptor family member NLRP12 was shown to suppress colorectal tumorigenesis, but the precise mechanism was unknown. Here, we demonstrate tha...

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Detalles Bibliográficos
Autores principales: Khan, Shahanshah, Kwak, Youn-Tae, Peng, Lan, Hu, Shuiqing, Cantarel, Brandi L., Lewis, Cheryl M., Gao, Yunpeng, Mani, Ram S., Kanneganti, Thirumala-Devi, Zaki, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541192/
https://www.ncbi.nlm.nih.gov/pubmed/37581937
http://dx.doi.org/10.1172/JCI166295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541192/
https://www.ncbi.nlm.nih.gov/pubmed/37581937
http://dx.doi.org/10.1172/JCI166295

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