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NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer
Colorectal cancer (CRC) at advanced stages is rarely curable, underscoring the importance of exploring the mechanism of CRC progression and invasion. NOD-like receptor family member NLRP12 was shown to suppress colorectal tumorigenesis, but the precise mechanism was unknown. Here, we demonstrate tha...
Autores principales: | Khan, Shahanshah, Kwak, Youn-Tae, Peng, Lan, Hu, Shuiqing, Cantarel, Brandi L., Lewis, Cheryl M., Gao, Yunpeng, Mani, Ram S., Kanneganti, Thirumala-Devi, Zaki, Hasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541192/ https://www.ncbi.nlm.nih.gov/pubmed/37581937 http://dx.doi.org/10.1172/JCI166295 |
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