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Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models

The adipose-derived hormone leptin acts via its receptor (LepRb) in the brain to control energy balance. A potentially unidentified population of GABAergic hypothalamic LepRb neurons plays key roles in the restraint of food intake and body weight by leptin. To identify markers for candidate populati...

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Detalles Bibliográficos
Autores principales: Rupp, Alan C., Tomlinson, Abigail J., Affinati, Alison H., Yacawych, Warren T., Duensing, Allison M., True, Cadence, Lindsley, Sarah R., Kirigiti, Melissa A., MacKenzie, Alexander, Polex-Wolf, Joseph, Li, Chien, Knudsen, Lotte Bjerre, Seeley, Randy J., Olson, David P., Kievit, Paul, Myers, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541203/
https://www.ncbi.nlm.nih.gov/pubmed/37581939
http://dx.doi.org/10.1172/JCI157515