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Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity

There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Ecc...

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Autores principales: Szűcs, Gergő, Pipicz, Márton, Szabó, Márton Richárd, Csont, Tamás, Török, László, Csonka, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541389/
https://www.ncbi.nlm.nih.gov/pubmed/37775653
http://dx.doi.org/10.1186/s40798-023-00596-2
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author Szűcs, Gergő
Pipicz, Márton
Szabó, Márton Richárd
Csont, Tamás
Török, László
Csonka, Csaba
author_facet Szűcs, Gergő
Pipicz, Márton
Szabó, Márton Richárd
Csont, Tamás
Török, László
Csonka, Csaba
author_sort Szűcs, Gergő
collection PubMed
description There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Eccentric contraction may lead to better power production characteristics of the muscle because eccentric contraction requires less energy and can result in higher tension. Therefore, it is an ideal tool in the rehabilitation program of patients. However, the complex metabolic effect (i.e., fat mass reduction, increased lipid oxidation, improvement in blood lipid profile, and increased insulin sensitivity) of the eccentric contraction alone has scarcely been investigated. This paper aims to review the current literature to provide information on whether eccentric contraction can influence metabolic health and body composition in T2DM or obesity. We also discussed the potential role of myokines in mediating the effects of eccentric exercise. A better understanding of the mechanism of eccentric training and particularly their participation in the regulation of metabolic diseases may widen their possible therapeutic use and, thereby, may support the fight against the leading global risks for mortality in the world.
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spelling pubmed-105413892023-10-01 Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity Szűcs, Gergő Pipicz, Márton Szabó, Márton Richárd Csont, Tamás Török, László Csonka, Csaba Sports Med Open Review Article There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Eccentric contraction may lead to better power production characteristics of the muscle because eccentric contraction requires less energy and can result in higher tension. Therefore, it is an ideal tool in the rehabilitation program of patients. However, the complex metabolic effect (i.e., fat mass reduction, increased lipid oxidation, improvement in blood lipid profile, and increased insulin sensitivity) of the eccentric contraction alone has scarcely been investigated. This paper aims to review the current literature to provide information on whether eccentric contraction can influence metabolic health and body composition in T2DM or obesity. We also discussed the potential role of myokines in mediating the effects of eccentric exercise. A better understanding of the mechanism of eccentric training and particularly their participation in the regulation of metabolic diseases may widen their possible therapeutic use and, thereby, may support the fight against the leading global risks for mortality in the world. Springer International Publishing 2023-09-29 /pmc/articles/PMC10541389/ /pubmed/37775653 http://dx.doi.org/10.1186/s40798-023-00596-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Szűcs, Gergő
Pipicz, Márton
Szabó, Márton Richárd
Csont, Tamás
Török, László
Csonka, Csaba
Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title_full Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title_fullStr Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title_full_unstemmed Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title_short Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity
title_sort effect of eccentric exercise on metabolic health in diabetes and obesity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541389/
https://www.ncbi.nlm.nih.gov/pubmed/37775653
http://dx.doi.org/10.1186/s40798-023-00596-2
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