Epidural Extramedullary Plasmacytoma Successfully Treated with Surgical Excision and Bortezomib, Cyclophosphamide and Dexamethasone

Plasma cell neoplasms are common, accounting for more than 1% of all malignancies. Its most common form is multiple myeloma, but others, such as extramedullary plasmacytoma (EMP), exist. Spinal cord compression secondary to these pathologies is not uncommon, however, adjacent bone involvement is usu...

Descripción completa

Detalles Bibliográficos
Autores principales: MARTIO, ARTUR EDUARDO, MIOTTO, GUILHERME JOSÉ, FILHO, PAULO MOACIR MESQUITA, CHAVES, WILLIAM SCHEFFER, KARAM, OCTÁVIO RUSCHEL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541513/
https://www.ncbi.nlm.nih.gov/pubmed/37786620
http://dx.doi.org/10.12865/CHSJ.49.02.288
Descripción
Sumario:Plasma cell neoplasms are common, accounting for more than 1% of all malignancies. Its most common form is multiple myeloma, but others, such as extramedullary plasmacytoma (EMP), exist. Spinal cord compression secondary to these pathologies is not uncommon, however, adjacent bone involvement is usually present. Spinal cord compression caused by isolated epidural EMP is extremely rare, with only one case reported to date. We describe the case of a 75-year-old female patient that presented with paraparesis, due to an isolated epidural EMP associated with light chain amyloidosis. She was treated with surgical decompression and neoadjuvant chemotherapy, and is currently with a 15-month disease-free period.

Ejemplares similares