Cargando…

Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons

The anterolateral system (ALS) is a major ascending pathway from the spinal cord that projects to multiple brain areas and underlies the perception of pain, itch and skin temperature. Despite its importance, our understanding of this system has been hampered by the considerable functional and molecu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bell, Andrew M., Utting, Charlotte, Dickie, Allen C., Kucharczyk, Mateusz W., Quillet, Raphaëlle, Gutierrez-Mecinas, Maria, Razlan, Aimi N.B., Cooper, Andrew H., Lan, Yuxuan, Hachisuka, Junichi, Weir, Greg A., Bannister, Kirsty, Watanabe, Masahiko, Kania, Artur, Hoon, Mark A., Macaulay, Iain C., Denk, Franziska, Todd, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541585/ https://www.ncbi.nlm.nih.gov/pubmed/37786726 http://dx.doi.org/10.1101/2023.08.20.553715

Ejemplares similares

Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line
por: Alsulaiman, Wafa A. A., et al.
Publicado: (2021)

Genetic evidence of the function of Phox2a-expressing anterolateral system neurons in the transmission of chronic pain
por: Zhang, Xinying, et al.
Publicado: (2023)

Characterisation of deep dorsal horn projection neurons in the spinal cord of the Phox2a::Cre mouse line
por: Kókai, Éva, et al.
Publicado: (2022)

Characterisation of NPFF-expressing neurons in the superficial dorsal horn of the mouse spinal cord
por: Quillet, Raphaëlle, et al.
Publicado: (2023)

Grpr expression defines a population of superficial dorsal horn vertical cells that have a role in both itch and pain
por: Polgár, Erika, et al.
Publicado: (2023)

Anterolateral knee biomechanics
por: Amis, Andrew A.
Publicado: (2017)

The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli
por: Kucharczyk, Mateusz W., et al.
Publicado: (2020)

Pioglitazone Inhibits the Expressions of p22(phox) and p47(phox) in Rat Mesangial Cells In Vitro
por: Wang, Shan, et al.
Publicado: (2014)

Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats
por: Sharma, Neeru M., et al.
Publicado: (2016)

Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes
por: Murata, Kazutaka, et al.
Publicado: (2010)

Hopes for the Future of Pain Control
por: Bannister, Kirsty, et al.
Publicado: (2017)

Developments in Understanding Diffuse Noxious Inhibitory Controls: Pharmacological Evidence from Pre-Clinical Research
por: Kucharczyk, Mateusz Wojciech, et al.
Publicado: (2021)

The Anterolateral Ligament is Not the Whole Story: Reconsidering the Form and Function of the Anterolateral Knee and its Contribution to Rotatory Knee Instability
por: Sheean, Andrew J., et al.
Publicado: (2018)

Substance P-expressing Neurons in the Superficial Dorsal Horn of the Mouse Spinal Cord: Insights into Their Functions and their Roles in Synaptic Circuits
por: Polgár, Erika, et al.
Publicado: (2020)

Proton Conduction through gp91(phox)
por: Henderson, Lydia M., et al.
Publicado: (2002)

Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
por: Zang, Jie, et al.
Publicado: (2023)

ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes
por: Tlili, Asma, et al.
Publicado: (2023)

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
Publicado: (1994)

Distinct brainstem to spinal cord noradrenergic pathways inversely regulate spinal neuronal activity
por: Kucharczyk, Mateusz W, et al.
Publicado: (2022)

A critical brainstem relay for mediation of diffuse noxious inhibitory controls
por: Kucharczyk, Mateusz W, et al.
Publicado: (2023)

Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons
por: Bourojeni, Farin B., et al.
Publicado: (2021)

Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
por: Boyle, Kieran A, et al.
Publicado: (2023)

Gene transfer and expression in human neutrophils. The phox homology domain of p47(phox )translocates to the plasma membrane but not to the membrane of mature phagosomes
por: Johnson, Jennifer L, et al.
Publicado: (2006)

Subcellular localisation of the p40(phox) component of NADPH oxidase involves direct interactions between the Phox homology domain and F-actin
por: Shao, Dongmin, et al.
Publicado: (2010)

An eponymous history of the anterolateral ligament complex of the knee
por: Morgan, Allison M., et al.
Publicado: (2022)

The emergence of phox-ER stress induced immunogenic apoptosis
por: Garg, Abhishek D., et al.
Publicado: (2012)

Contributions of PHOX2B in the Pathogenesis of Hirschsprung Disease
por: Fernández, Raquel María, et al.
Publicado: (2013)

PHOX2B is a suppressor of neuroblastoma metastasis
por: Naftali, Osnat, et al.
Publicado: (2016)

PhoX: An IMAC-Enrichable Cross-Linking Reagent
por: Steigenberger, Barbara, et al.
Publicado: (2019)

Role of the Anterior Cruciate Ligament, Anterolateral Complex, and Lateral Meniscus Posterior Root in Anterolateral Rotatory Knee Instability: A Biomechanical Study
por: Willinger, Lukas, et al.
Publicado: (2023)

The anterolateral approach to the proximal humerus for nonunions and delayed unions
por: Hettrich, Carolyn M., et al.
Publicado: (2011)

An Overview of Clinically Relevant Biomechanics of the Anterolateral Structures of the Knee
por: Kennedy, Mitchell I., et al.
Publicado: (2018)

Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox
Publicado: (1996)

New NADPH Oxidase 2 Inhibitors Display Potent Activity against Oxidative Stress by Targeting p22(phox)-p47(phox) Interactions
por: Treuer, Adriana V., et al.
Publicado: (2023)

The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences
por: Daggett, Matt, et al.
Publicado: (2017)

The Stage-Specific Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced Bone Pain
por: Kucharczyk, Mateusz Wojciech, et al.
Publicado: (2020)

Liposome-Mediated Cellular Delivery of Active gp91(phox)
por: Marques, Bruno, et al.
Publicado: (2007)

NLO Theoretical Predictions for Photon Measurements Using the PHOX Generators
por: Blair, R, et al.
Publicado: (2011)

Colitis susceptibility in p47(phox−/−) mice is mediated by the microbiome
por: Falcone, E. Liana, et al.
Publicado: (2016)

p47phox contributes to albuminuria and kidney fibrosis in mice
por: Wang, Hongtao, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_g6dcppais26bh18oc71t3cjt11