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Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

BACKGROUND: In recent years, the development of BMSCs-derived exosomes (EXO) for the treatment of osteosarcoma (OS) is a safe and promising modality for OS treatment, which can effectively deliver drugs to tumor cells in vivo. However, the differences in the drugs carried, and the binding of EXOs to...

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Detalles Bibliográficos
Autores principales:	Chen, Wenkai, Li, Zongguang, Yu, Naichun, Zhang, Linlin, Li, Hongyu, Chen, Yongjie, Gong, Fengqing, Lin, Wenping, He, Xu, Wang, Siyuan, Wu, Yue, Ji, Guangrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541697/ https://www.ncbi.nlm.nih.gov/pubmed/37775799 http://dx.doi.org/10.1186/s12951-023-02129-1

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