Mitochondrially targeted tamoxifen as anticancer therapy: case series of patients with renal cell carcinoma treated in a phase I/Ib clinical trial

Mitochondrially targeted anticancer drugs (mitocans) that disrupt the energy-producing systems of cancer are emerging as new potential therapeutics. Mitochondrially targeted tamoxifen (MitoTam), an inhibitor of mitochondrial respiration respiratory complex I, is a first-in-class mitocan that was tes...

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Detalles Bibliográficos
Autores principales: Bielcikova, Zuzana, Werner, Lukas, Stursa, Jan, Cerny, Vladimir, Krizova, Ludmila, Spacek, Jan, Hlousek, Stanislav, Vocka, Michal, Bartosova, Olga, Pesta, Michal, Kolostova, Katarina, Klezl, Petr, Bobek, Vladimir, Truksa, Jaroslav, Stemberkova-Hubackova, Sona, Petruzelka, Lubos, Michalek, Pavel, Neuzil, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541747/
https://www.ncbi.nlm.nih.gov/pubmed/37786538
http://dx.doi.org/10.1177/17588359231197957

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