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Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming

In optic neuropathies, including glaucoma, retinal ganglion cells (RGCs) die. Cell transplantation and endogenous regeneration offer strategies for retinal repair, however, developmental programs required for this to succeed are incompletely understood. To address this, we explored cellular reprogra...

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Detalles Bibliográficos
Autores principales: Agarwal, Devansh, Dash, Nicholas, Mazo, Kevin W., Chopra, Manan, Avila, Maria P., Patel, Amit, Wong, Ryan M., Jia, Cairang, Do, Hope, Cheng, Jie, Chiang, Colette, Jurlina, Shawna L., Roshan, Mona, Perry, Michael W., Rho, Jong M., Broyer, Risa, Lee, Cassidy D., Weinreb, Robert N., Gavrilovici, Cezar, Oesch, Nicholas W., Welsbie, Derek S., Wahlin, Karl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541876/
https://www.ncbi.nlm.nih.gov/pubmed/37773257
http://dx.doi.org/10.1038/s41536-023-00327-x