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Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming
In optic neuropathies, including glaucoma, retinal ganglion cells (RGCs) die. Cell transplantation and endogenous regeneration offer strategies for retinal repair, however, developmental programs required for this to succeed are incompletely understood. To address this, we explored cellular reprogra...
Autores principales: | Agarwal, Devansh, Dash, Nicholas, Mazo, Kevin W., Chopra, Manan, Avila, Maria P., Patel, Amit, Wong, Ryan M., Jia, Cairang, Do, Hope, Cheng, Jie, Chiang, Colette, Jurlina, Shawna L., Roshan, Mona, Perry, Michael W., Rho, Jong M., Broyer, Risa, Lee, Cassidy D., Weinreb, Robert N., Gavrilovici, Cezar, Oesch, Nicholas W., Welsbie, Derek S., Wahlin, Karl J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541876/ https://www.ncbi.nlm.nih.gov/pubmed/37773257 http://dx.doi.org/10.1038/s41536-023-00327-x |
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