Alternate splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer

Aberrant mitochondrial fission/fusion dynamics have previously been reported in cancer cells. While post translational modifications are known regulators of GTPases of the mitochondrial fission/fusion machinery, we show for the first time that alternate splice variants of the fission protein Drp1 (D...

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Detalles Bibliográficos
Autores principales: Javed, Zaineb, Hui Shin, Dong, Pan, Weihua, White, Sierra R., Soo Kim, Yeon, Taher Elhaw, Amal, Kamlapurkar, Shriya, Cheng, Ya-Yun, Benson, J Cory, Emam Abdelnaby, Ahmed, Phaeton, Rebecca, Wang, Hong-Gang, Yang, Shengyu, Sullivan, Mara L.G., Watkins, Simon C., Mullett, Steven J., Gelhaus, Stacy L., Lee, Nam, Coffman, Lan G., Aird, Katherine M., Trebak, Mohamed, Mythreye, Karthikeyan, Walter, Vonn, Hempel, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542115/
https://www.ncbi.nlm.nih.gov/pubmed/37790404
http://dx.doi.org/10.1101/2023.09.20.558501

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