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Mechanisms of resistance to EGFR-targeted therapies in colorectal cancer: more than just genetics

The development of acquired resistance to anti-EGFR therapies remains poorly understood, with most research to date exploring, and trying to overcome, various genomic mechanisms of resistance. However, recent work supports a model of resistance whereby transcriptomic mechanisms of resistance predomi...

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Detalles Bibliográficos
Autores principales:	Parseghian, Christine, Eluri, Madhulika, Kopetz, Scott, Raghav, Kanwal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542118/ https://www.ncbi.nlm.nih.gov/pubmed/37791069 http://dx.doi.org/10.3389/fcell.2023.1176657

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