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Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBPα
Pioneer transcription factors are vital for cell fate changes. PU.1 and C/EBPα work together to regulate hematopoietic stem cell differentiation. However, how they recognize in vivo nucleosomal DNA targets remain elusive. Here we report the structures of the nucleosome containing the mouse genomic C...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542146/ https://www.ncbi.nlm.nih.gov/pubmed/37790476 http://dx.doi.org/10.1101/2023.08.25.554718 |