Effects of protein G-quadruplex interactions on phase transitions and protein aggregation

We show that human protein Znf706 interacts specifically with stable, non-canonical nucleic acid structures known as G-quadruplexes. Znf706, though only 76 residues long, is comprised of two distinct domains, one disordered and one ordered. The disordered domain is homologous to the SERF family of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahoo, Bikash R., Kocman, Vojč, Clark, Nathan, Myers, Nikhil, Deng, Xiexiong, Wong, Ee L., Yang, Harry J., Kotar, Anita, Guzman, Bryan B., Dominguez, Daniel, Plavec, Janez, Bardwell, James C.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542165/
https://www.ncbi.nlm.nih.gov/pubmed/37790366
http://dx.doi.org/10.1101/2023.09.21.558871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542165/
https://www.ncbi.nlm.nih.gov/pubmed/37790366
http://dx.doi.org/10.1101/2023.09.21.558871

Ejemplares similares