Effects of protein G-quadruplex interactions on phase transitions and protein aggregation

We show that human protein Znf706 interacts specifically with stable, non-canonical nucleic acid structures known as G-quadruplexes. Znf706, though only 76 residues long, is comprised of two distinct domains, one disordered and one ordered. The disordered domain is homologous to the SERF family of p...

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Detalles Bibliográficos
Autores principales: Sahoo, Bikash R., Kocman, Vojč, Clark, Nathan, Myers, Nikhil, Deng, Xiexiong, Wong, Ee L., Yang, Harry J., Kotar, Anita, Guzman, Bryan B., Dominguez, Daniel, Plavec, Janez, Bardwell, James C.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542165/
https://www.ncbi.nlm.nih.gov/pubmed/37790366
http://dx.doi.org/10.1101/2023.09.21.558871

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