50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective

Fifty years have now passed since Parry and Squire proposed a detailed structural model that explained how tropomyosin, mediated by troponin, played a steric-blocking role in the regulation of vertebrate skeletal muscle. In this Special Issue dedicated to the memory of John Squire it is an opportune...

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Detalles Bibliográficos
Autor principal: Parry, David A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542282/
https://www.ncbi.nlm.nih.gov/pubmed/35789471
http://dx.doi.org/10.1007/s10974-022-09619-z
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author Parry, David A. D.
author_facet Parry, David A. D.
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description Fifty years have now passed since Parry and Squire proposed a detailed structural model that explained how tropomyosin, mediated by troponin, played a steric-blocking role in the regulation of vertebrate skeletal muscle. In this Special Issue dedicated to the memory of John Squire it is an opportune time to look back on this research and to appreciate John’s key contributions. A review is also presented of a selection of the developments and insights into muscle regulation that have occurred in the years since this proposal was formulated.
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spelling pubmed-105422822023-10-03 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective Parry, David A. D. J Muscle Res Cell Motil Review Fifty years have now passed since Parry and Squire proposed a detailed structural model that explained how tropomyosin, mediated by troponin, played a steric-blocking role in the regulation of vertebrate skeletal muscle. In this Special Issue dedicated to the memory of John Squire it is an opportune time to look back on this research and to appreciate John’s key contributions. A review is also presented of a selection of the developments and insights into muscle regulation that have occurred in the years since this proposal was formulated. Springer International Publishing 2022-07-05 2023 /pmc/articles/PMC10542282/ /pubmed/35789471 http://dx.doi.org/10.1007/s10974-022-09619-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Parry, David A. D.
50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title_full 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title_fullStr 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title_full_unstemmed 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title_short 50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
title_sort 50 years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542282/
https://www.ncbi.nlm.nih.gov/pubmed/35789471
http://dx.doi.org/10.1007/s10974-022-09619-z
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