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Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain

Selective serotonin reuptake inhibitors (SSRI) are common first-line treatments for major depression. However, a significant number of depressed patients do not respond adequately to these pharmacological treatments. In the present preclinical study, we demonstrate that organic cation transporter 2...

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Detalles Bibliográficos
Autores principales:	Orrico-Sanchez, Alejandro, Guiard, Bruno P., Manta, Stella, Callebert, Jacques, Launay, Jean-Marie, Louis, Franck, Paccard, Antoine, Gruszczynski, Carole, Betancur, Catalina, Vialou, Vincent, Gautron, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542329/ https://www.ncbi.nlm.nih.gov/pubmed/37775532 http://dx.doi.org/10.1038/s41398-023-02596-y

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