mRNA-LNP vaccination-based immunotherapy augments CD8(+) T cell responses against HPV-positive oropharyngeal cancer

Although mRNA vaccines are known as potent activators of antigen-specific immune responses against infectious diseases, limited understanding of how they drive the functional commitment of CD8(+) T cells in tumor microenvironment (TME) and secondary lymphoid organs hinders their broader application...

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Detalles Bibliográficos
Autores principales: Qiu, Ke, Duan, Xing, Mao, Minzi, Song, Yao, Rao, Yufang, Cheng, Danni, Feng, Lan, Shao, Xiuli, Jiang, Chuanhuan, Huang, Hai, Wang, Yan, Li, Huifang, Chen, Xuemei, Wu, Sisi, Luo, Dan, Chen, Fei, Peng, Xingchen, Zheng, Yongbo, Wang, Haiyang, Liu, Jun, Zhao, Yu, Song, Xiangrong, Ren, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542330/
https://www.ncbi.nlm.nih.gov/pubmed/37773254
http://dx.doi.org/10.1038/s41541-023-00733-8

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