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“Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A”

Antibody engineering technology is at the forefront of therapeutic antibody development. The primary goal for engineering a therapeutic antibody is the generation of an antibody with a desired specificity, affinity, function, and developability profile. Mature antibodies are considered antigen speci...

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Detalles Bibliográficos
Autores principales:	Fischman, Sharon, Levin, Itay, Rondeau, Jean-Michel, Štrajbl, Marek, Lehmann, Sylvie, Huber, Thomas, Nimrod, Guy, Cebe, Régis, Omer, Dotan, Kovarik, Jiri, Bernstein, Shmuel, Sasson, Yehezkel, Demishtein, Alik, Shlamkovich, Tomer, Bluvshtein, Olga, Grossman, Noam, Barak-Fuchs, Reut, Zhenin, Michael, Fastman, Yair, Twito, Shir, Vana, Tal, Zur, Nevet, Ofran, Yanay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542344/ https://www.ncbi.nlm.nih.gov/pubmed/37773269 http://dx.doi.org/10.1038/s42003-023-05369-x

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