Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex

In Saccharomyces cerevisiae, cryptic transcription at the coding region is prevented by the activity of Sin3 histone deacetylase (HDAC) complex Rpd3S, which is carried by the transcribing RNA polymerase II (RNAPII) to deacetylate and stabilize chromatin. Despite its fundamental importance, the mecha...

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Detalles Bibliográficos
Autores principales: Dong, Shuqi, Li, Huadong, Wang, Meilin, Rasheed, Nadia, Zou, Binqian, Gao, Xijie, Guan, Jiali, Li, Weijie, Zhang, Jiale, Wang, Chi, Zhou, Ningkun, Shi, Xue, Li, Mei, Zhou, Min, Huang, Junfeng, Li, He, Zhang, Ying, Wong, Koon Ho, Zhang, Xiaofei, Chao, William Chong Hang, He, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542350/
https://www.ncbi.nlm.nih.gov/pubmed/37666978
http://dx.doi.org/10.1038/s41422-023-00869-1

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