Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation

Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity of the intestinal epithelium during aging. However, the impact of intestinal microbiota on ISCs in this process is unclear. Here, using premature aging mice (telomerase RNA component knockout, Terc(−/−)), na...

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Detalles Bibliográficos
Autores principales: Qi, Yadong, He, Jiamin, Zhang, Yawen, Ge, Qiwei, Wang, Qiwen, Chen, Luyi, Xu, Jilei, Wang, Lan, Chen, Xueqin, Jia, Dingjiacheng, Lin, Yifeng, Xu, Chaochao, Zhang, Ying, Hou, Tongyao, Si, Jianmin, Chen, Shujie, Wang, Liangjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542354/
https://www.ncbi.nlm.nih.gov/pubmed/37777508
http://dx.doi.org/10.1038/s41467-023-41827-0

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