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An unbiased proteomic analysis of PAD4 in human monocytes: novel substrates, binding partners and subcellular localizations

Peptidylarginine deiminase IV (PAD4) post-translationally converts arginine residues in proteins to citrullines and is implicated in playing a central role in the pathogenesis of several diseases. Although PAD4 was historically thought to be a nuclear enzyme, recent evidence has revealed a more comp...

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Detalles Bibliográficos
Autores principales: Thomas, Mekha A., Kim, Seok-Young, Curran, Ashley M., Smith, Barbara, Antiochos, Brendan, Na, Chan Hyun, Darrah, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542449/
https://www.ncbi.nlm.nih.gov/pubmed/37778379
http://dx.doi.org/10.1098/rstb.2022.0477