Unsupervised [(18)F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

PURPOSE: Several [(18)F]Flortaucipir cutoffs have been proposed for tau PET positivity (T(+)) in Alzheimer’s disease (AD), but none were data-driven. The aim of this study was to establish and validate unsupervised T(+) cutoffs by applying Gaussian mixture models (GMM). METHODS: Amyloid negative (A(...

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Detalles Bibliográficos
Autores principales: Quattrini, Giulia, Ferrari, Clarissa, Pievani, Michela, Geviti, Andrea, Ribaldi, Federica, Scheffler, Max, Frisoni, Giovanni B, Garibotto, Valentina, Marizzoni, Moira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542510/
https://www.ncbi.nlm.nih.gov/pubmed/37272955
http://dx.doi.org/10.1007/s00259-023-06280-7

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