Computational design of sequence-specific DNA-binding proteins

Sequence-specific DNA-binding proteins (DBPs) play critical roles in biology and biotechnology, and there has been considerable interest in the engineering of DBPs with new or altered specificities for genome editing and other applications. While there has been some success in reprogramming naturall...

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Detalles Bibliográficos
Autores principales: Glasscock, Cameron J., Pecoraro, Robert, McHugh, Ryan, Doyle, Lindsey A., Chen, Wei, Boivin, Olivier, Lonnquist, Beau, Na, Emily, Politanska, Yuliya, Haddox, Hugh K., Cox, David, Norn, Christoffer, Coventry, Brian, Goreshnik, Inna, Vafeados, Dionne, Lee, Gyu Rie, Gordan, Raluca, Stoddard, Barry L., DiMaio, Frank, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542524/
https://www.ncbi.nlm.nih.gov/pubmed/37790440
http://dx.doi.org/10.1101/2023.09.20.558720

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