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Characterization and optimization of variability in a human colonic epithelium culture model

Animal models have historically been poor preclinical predictors of gastrointestinal (GI) directed therapeutic efficacy and drug-induced GI toxicity. Human stem and primary cell-derived culture systems are a major focus of efforts to create biologically relevant models that enhance preclinical predi...

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Detalles Bibliográficos
Autores principales:	Pike, Colleen M., Zwarycz, Bailey, McQueen, Bryan E., Castillo, Mariana, Barron, Catherine, Morowitz, Jeremy M., Levi, James A., Phadke, Dhiral, Balik-Meisner, Michele, Mav, Deepak, Shah, Ruchir, Glasspoole, Danielle L. Cunningham, Laetham, Ron, Thelin, William, Bunger, Maureen K., Boazak, Elizabeth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542543/ https://www.ncbi.nlm.nih.gov/pubmed/37790345 http://dx.doi.org/10.1101/2023.09.22.559007

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