Simulating the conformational dynamics of the ATPase complex on proteasome using its free-energy landscape

The AAA+ ATPase complex on proteasome powers its functions through a series of intricate conformational transitions. Here, we describe a procedure to simulate the conformational dynamics of the proteasomal ATPase complex. We first empirically determined the free-energy landscape (FEL) of proteasome...

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Detalles Bibliográficos
Autores principales: Fang, Rui, Lu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542641/
https://www.ncbi.nlm.nih.gov/pubmed/37768828
http://dx.doi.org/10.1016/j.xpro.2023.102182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542641/
https://www.ncbi.nlm.nih.gov/pubmed/37768828
http://dx.doi.org/10.1016/j.xpro.2023.102182

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