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Estimating residual undifferentiated cells in human chemically induced pluripotent stem cell derived islets using lncRNA as biomarkers

Human pluripotent stem cells (hPSCs) can generate insulin-producing beta cells for diabetes treatment, but residual undifferentiated cells may cause tumors. We developed a highly sensitive assay to detect these cells in islet cells derived from human chemically induced pluripotent stem cells (hCiPSC...

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Detalles Bibliográficos
Autores principales: Wu, Yandan, Zhang, Zhenzhen, Wu, Shuangshuang, Chen, Zhaolong, Pu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542758/
https://www.ncbi.nlm.nih.gov/pubmed/37777562
http://dx.doi.org/10.1038/s41598-023-43798-0