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Estimating residual undifferentiated cells in human chemically induced pluripotent stem cell derived islets using lncRNA as biomarkers
Human pluripotent stem cells (hPSCs) can generate insulin-producing beta cells for diabetes treatment, but residual undifferentiated cells may cause tumors. We developed a highly sensitive assay to detect these cells in islet cells derived from human chemically induced pluripotent stem cells (hCiPSC...
Autores principales: | Wu, Yandan, Zhang, Zhenzhen, Wu, Shuangshuang, Chen, Zhaolong, Pu, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542758/ https://www.ncbi.nlm.nih.gov/pubmed/37777562 http://dx.doi.org/10.1038/s41598-023-43798-0 |
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