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STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia

Immunotherapy is a revolutionized therapeutic strategy for tumor treatment attributing to the rapid development of genomics and immunology, and immune checkpoint inhibitors have successfully achieved responses in numbers of tumor types, including hematopoietic malignancy. However, acute myeloid leuk...

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Detalles Bibliográficos
Autores principales:	Huang, Ze-Wei, Zhang, Xue-Ning, Zhang, Ling, Liu, Ling-Ling, Zhang, Jing-Wen, Sun, Yu-Xiang, Xu, Jue-Qiong, Liu, Quentin, Long, Zi-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542808/ https://www.ncbi.nlm.nih.gov/pubmed/37777506 http://dx.doi.org/10.1038/s41392-023-01605-2

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