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Aging-induced pseudouridine synthase 10 impairs hematopoietic stem cells

Aged hematopoietic stem cells (HSC) exhibit compromised reconstitution capacity and differentiation-bias towards myeloid lineage, however, the molecular mechanism behind it remains not fully understood. In this study, we observed that the expression of pseudouridine (Ψ) synthase 10 is increased in a...

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Detalles Bibliográficos
Autores principales:	Wang, Yuqian, Zhang, Zhenzhen, He, Hanqing, Song, Jinghui, Cui, Yang, Chen, Yunan, Zhuang, Yuan, Zhang, Xiaoting, Li, Mo, Zhang, Xinxiang, Zhang, Michael Q., Shi, Minglei, Yi, Chengqi, Wang, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2023
Materias:	Article - Hematopoiesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542847/ https://www.ncbi.nlm.nih.gov/pubmed/37165848 http://dx.doi.org/10.3324/haematol.2022.282211

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