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Early clinical indicators of acute kidney injury caused by administering high-dose methotrexate therapy to juvenile pigs

INTRODUCTION: Early identification of compromised renal clearance caused by high-dose methotrexate (HDMTX) is essential for initiating timely interventions that can reduce acute kidney injury and MTX-induced systemic toxicity. METHODS: We induced acute kidney injury (AKI) by infusing 42 juvenile pig...

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Detalles Bibliográficos
Autores principales:	Buddington, Randal K., Wong, Thomas, Buddington, Karyl K., Mikkelsen, Torben S., Cao, Xueyuan, Howard, Scott C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nephrology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542898/ https://www.ncbi.nlm.nih.gov/pubmed/37790293 http://dx.doi.org/10.3389/fneph.2023.1193494

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