Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function

BACKGROUND: This study was aimed to evaluate the efficacy of pramipexole combined with ganglioside for PD treatment and pramipexole monotherapy, so as to provide reference for clinical practice. METHODS: 61 PD patients selected from June 2019 to December 2020 at our hospital were divided into two gr...

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Detalles Bibliográficos
Autores principales: Li, Xinna, Han, Peihai, Liu, Mengjiao, Li, Xiaowen, Xue, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia, Belgrade 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543131/
https://www.ncbi.nlm.nih.gov/pubmed/37790213
http://dx.doi.org/10.5937/jomb0-42550
Descripción
Sumario:BACKGROUND: This study was aimed to evaluate the efficacy of pramipexole combined with ganglioside for PD treatment and pramipexole monotherapy, so as to provide reference for clinical practice. METHODS: 61 PD patients selected from June 2019 to December 2020 at our hospital were divided into two groups. The control group (n=31) was given dopasizide oral treatment, and the treatment group (n=30) was given ganglioside combined with pramipexole. The clinical efficacy, adverse reactions, motor function scores, UPDRS scores, PDQ-39 scale scores, TNF-a levels, and related serum factor levels were measured in this study.

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