Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function

BACKGROUND: This study was aimed to evaluate the efficacy of pramipexole combined with ganglioside for PD treatment and pramipexole monotherapy, so as to provide reference for clinical practice. METHODS: 61 PD patients selected from June 2019 to December 2020 at our hospital were divided into two gr...

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Detalles Bibliográficos
Autores principales: Li, Xinna, Han, Peihai, Liu, Mengjiao, Li, Xiaowen, Xue, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia, Belgrade 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543131/
https://www.ncbi.nlm.nih.gov/pubmed/37790213
http://dx.doi.org/10.5937/jomb0-42550
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author Li, Xinna
Han, Peihai
Liu, Mengjiao
Li, Xiaowen
Xue, Shuai
author_facet Li, Xinna
Han, Peihai
Liu, Mengjiao
Li, Xiaowen
Xue, Shuai
author_sort Li, Xinna
collection PubMed
description BACKGROUND: This study was aimed to evaluate the efficacy of pramipexole combined with ganglioside for PD treatment and pramipexole monotherapy, so as to provide reference for clinical practice. METHODS: 61 PD patients selected from June 2019 to December 2020 at our hospital were divided into two groups. The control group (n=31) was given dopasizide oral treatment, and the treatment group (n=30) was given ganglioside combined with pramipexole. The clinical efficacy, adverse reactions, motor function scores, UPDRS scores, PDQ-39 scale scores, TNF-a levels, and related serum factor levels were measured in this study.
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spelling pubmed-105431312023-10-03 Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function Li, Xinna Han, Peihai Liu, Mengjiao Li, Xiaowen Xue, Shuai J Med Biochem Original Paper BACKGROUND: This study was aimed to evaluate the efficacy of pramipexole combined with ganglioside for PD treatment and pramipexole monotherapy, so as to provide reference for clinical practice. METHODS: 61 PD patients selected from June 2019 to December 2020 at our hospital were divided into two groups. The control group (n=31) was given dopasizide oral treatment, and the treatment group (n=30) was given ganglioside combined with pramipexole. The clinical efficacy, adverse reactions, motor function scores, UPDRS scores, PDQ-39 scale scores, TNF-a levels, and related serum factor levels were measured in this study. Society of Medical Biochemists of Serbia, Belgrade 2023-08-25 2023-08-25 /pmc/articles/PMC10543131/ /pubmed/37790213 http://dx.doi.org/10.5937/jomb0-42550 Text en 2023 Xinna Li, Peihai Han, Mengjiao Liu, Xiaowen Li, Shuai Xue, published by CEON/CEES https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License.
spellingShingle Original Paper
Li, Xinna
Han, Peihai
Liu, Mengjiao
Li, Xiaowen
Xue, Shuai
Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title_full Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title_fullStr Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title_full_unstemmed Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title_short Effect of Ganglioside combined with pramexol in the treatment of Parkinson's disease and its effect on motor function
title_sort effect of ganglioside combined with pramexol in the treatment of parkinson's disease and its effect on motor function
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543131/
https://www.ncbi.nlm.nih.gov/pubmed/37790213
http://dx.doi.org/10.5937/jomb0-42550
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