JNKs protect from cholestatic liver disease progression by modulating Apelin signalling

BACKGROUND & AIMS: Cholestatic liver injury is associated with c-Jun N-terminal kinases (JNK) activation in distinct cell types. Its hepatocyte-specific function during cholestasis, however, has not yet been established. Therefore, in our present study, we investigated the role of JNK1/2 during...

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Detalles Bibliográficos
Autores principales: Mohamed, Mohamed Ramadan, Haybaeck, Johannes, Wu, Hanghang, Su, Huan, Bartneck, Matthias, Lin, Cheng, Boekschoten, Mark V., Boor, Peter, Goeppert, Benjamin, Rupp, Christian, Strnad, Pavel, Davis, Roger J., Cubero, Francisco Javier, Trautwein, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543210/
https://www.ncbi.nlm.nih.gov/pubmed/37791376
http://dx.doi.org/10.1016/j.jhepr.2023.100854

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