Loss of Bmp2 impairs odontogenesis via dysregulating pAkt/pErk/GCN5/Dlx3/Sp7

BMP2 signaling plays a pivotal role in odontoblast differentiation and maturation during odontogenesis. Teeth lacking Bmp2 exhibit a morphology reminiscent of dentinogenesis imperfecta (DGI), associated with mutations in dentin matrix protein 1 (DMP1) and dentin sialophosphoprotein (DSPP) genes. Mec...

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Detalles Bibliográficos
Autores principales: Chen, Shuo, Wang, Feng, Yang, Guobin, Yuan, Guohua, Liu, Mengmeng, Goldman, Graham, harris, stephen, Wang, Wei, Chen, Zhi, Mary, MacDougall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543288/
https://www.ncbi.nlm.nih.gov/pubmed/37790473
http://dx.doi.org/10.21203/rs.3.rs-3299295/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543288/
https://www.ncbi.nlm.nih.gov/pubmed/37790473
http://dx.doi.org/10.21203/rs.3.rs-3299295/v1

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