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Loss of Bmp2 impairs odontogenesis via dysregulating pAkt/pErk/GCN5/Dlx3/Sp7

BMP2 signaling plays a pivotal role in odontoblast differentiation and maturation during odontogenesis. Teeth lacking Bmp2 exhibit a morphology reminiscent of dentinogenesis imperfecta (DGI), associated with mutations in dentin matrix protein 1 (DMP1) and dentin sialophosphoprotein (DSPP) genes. Mec...

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Detalles Bibliográficos
Autores principales:	Chen, Shuo, Wang, Feng, Yang, Guobin, Yuan, Guohua, Liu, Mengmeng, Goldman, Graham, harris, stephen, Wang, Wei, Chen, Zhi, Mary, MacDougall
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543288/ https://www.ncbi.nlm.nih.gov/pubmed/37790473 http://dx.doi.org/10.21203/rs.3.rs-3299295/v1

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