Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations

SYNGAP1 is a critical gene for neuronal development, synaptic structure, and function. Although rare, the disruption of SYNGAP1 directly causes a genetically identifiable neurodevelopmental disorder (NDD) called SYNGAP1 -related intellectual disability. Without functional SynGAP1 protein, patients p...

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Detalles Bibliográficos
Autores principales: Silverman, Jill L., Fenton, Timothy, Haouchine, Olivia, Hallam, Elizabeth, Smith, Emily, Jackson, Kiya, Rahbarian, Darlene, Canales, Cesar, Adhikari, Anna, Nord, Alex, Ben-Shalom, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543290/
https://www.ncbi.nlm.nih.gov/pubmed/37790402
http://dx.doi.org/10.21203/rs.3.rs-3246655/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543290/
https://www.ncbi.nlm.nih.gov/pubmed/37790402
http://dx.doi.org/10.21203/rs.3.rs-3246655/v1

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