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MicroRNA-125a-5p regulates the effect of Tregs on Th1 and Th17 through targeting ETS-1/STAT3 in psoriasis

BACKGROUND: Psoriasis is an inflammatory disease mediated by helper T (Th)17 and Th1 cells. MicroRNA-125a (miR-125a) is reduced in the lesional skin of psoriatic patients. However, the mechanism by which miR-125a participates in psoriasis remains unclear. METHODS: The levels of miR-125a-5p and its d...

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Detalles Bibliográficos
Autores principales: Yan, Kexiang, Zhang, Fuxin, Ren, Jie, Huang, Qiong, Yawalkar, Nikhil, Han, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543306/
https://www.ncbi.nlm.nih.gov/pubmed/37773129
http://dx.doi.org/10.1186/s12967-023-04427-6